8-oxo-2’-deoxyguanosine (OdG), a mutated form of the DNA nucleotide 2’-deoxyguanosine (dG), is formed when dG is oxidized at the C8 position by reactive oxygen species. dG base pairs with 2’-deoxycytosine (dC), promoting correct DNA replication, but OdG can base pair with both dC and 2’-deoxyadenosine (dA). If OdG is paired with dA, the subsequent round of replication results in a point mutation, specifically a dG to dT transversion.