Vinamidinium salts and β-chloroenals were utilized for the development of two synthetic routes towards the biologically active marine alkaloid Lamellarin G trimethyl ether. Both routes culminated at a key intermediate previously prepared by Wolfgang Steglich and co-workers in their total synthesis of Lamellarin G trimethyl ether. The route employing vinamidinium salts reached the Steglich synthon in ten steps and is modular in nature, making it amenable for structure activity relationship studies.